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The controlled pH range supports: Solubility of many lyophilized compounds

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The gels were then imaged using second harmonic generation microscopy to determine fibrilar collagen as previously described [27]

This matters practically for EU research teams because most pre-clinical peptide research protocols require repeated dosing over days or weeks from the same reconstituted stock and the cost, time, and wastage of reconstituting fresh vials for every single administration makes unpreserved water impractical as a primary reconstitution solvent for the majority of peptide research applications